Georgios (George) Mentzelopoulos
Logo PhD Student @ University of Pennsylvania
TL;DR

I am a fifth (and final) year PhD student in Bioengineering at the University of Pennsylvania, advised by Dr. Flavia Vitale, in the Center for Neuroengineering and Therapeutics. During my PhD, I have obtained extensive experience working with big datasets and developing machine/deep learning frameworks with applications in computational neuroscience and brain computer interfaces. My work has been published at top-tier AI conferences (NeurIPS) and journals (Science Translational Medicine).

Current Projects

Multi-patient neural decoding from sEEG. I am currently developing methods to enable cross patient neural decoding from stereotactic EEG data. Currently, neural decoding based on sEEG is designed to be patient-specific, due to the challenge of integrating the heterogenous data across patients, where each is implanted with a variable number of electrodes placed at distinct locations in their brain. Those single-patient approaches, however, are cumbersome, expensive, and don't scale. To combat this, I am leveraging the versatility of transformers to create unified models for sEEG decoding that generalize across patients, despite the number and placement of electrodes in each patient's brain. This approach enables me to combine datasets collected across multiple patients and medical centers, to train more expressive models on orders of magnitude more data. The goal of this work is to enable robust, high-performance neural decoding from sEEG in a scalable way. [Project Page]

Energy efficient neural decoding from microelectrode arrays. I am developing energy efficient neural decoding methods for microelectrode array based brain computer interfaces (BCIs). BCIs have revolutionized the quality of life of people suffering from neurological disorders by enabling them to control computers with their thoughts, ultimately restoring their digital freedom. While extremely helpful, most BCIs rely on artificial neural networks (ANNs) that are power hungry, requiring users to recharge their BCI every few hours, which is impractical and frustrating. To combat this, I am developing neural decoders based on spiking neural networks, which are very energy efficient compared to ANNs when deployed on neuromorphic hardware. The goal of this work is to enable high-performance, energy efficient neural decoding from microelectrode arrays, to enable day long BCI use without the frustrating need for frequent recharging.

Looking for full-time opportunities

I am looking for full-time opportunities starting September 2025. I enjoy tackling multidisciplinary challenges and aspire to work in the space of AI/ML with applications in neural interfaces, AR/VR, and/or finance.


Education
  • University of Pennsylvania
    University of Pennsylvania
    PhD Bioengineering ⌛
    MSE Robotics 🎓
    Sep. 2020 - present
  • University of Michigan
    University of Michigan
    BSE Electrical Engineering 🎓
    BSE Biomedical Engineering 🎓
    Sep. 2016 - Jun. 2020
Experience
  • Neuralink
    Neuralink
    Data Science Intern
    June. 2022 - Nov. 2022
Honors & Awards
  • Onassis Foundation Graduate Student Scholarship ($36K)
    2022-2025
  • A. G. Leventis Foundation Graduate Student Scholarship ($36K)
    2022-2025
News
2024
Our paper "Neural decoding from stereotactic EEG: accounting for electrode variability across subjects" has been accepted for publication @ NeurIPS 2024 🎉. See you in Vancouver 🏔 🍁.
Sep 25
Our paper "TMS-induced phase resets depend on TMS intensity and EEG phase" has been accepted for publication in the Journal of Neural Engineering 🎉.
Sep 25
I am assisting Dr. Pratik Chaudhari teaching the graduate level course "Principles of Deep Learning" during the Fall 2024 semester 🤖 💻.
Aug 27
My scholarship from the A. G. Leventis Foundation got renewed for the 3rd consecutive year 🪙.
Jul 29
Selected Publications (view all )
Neural decoding from stereotactic EEG: accounting for electrode variability across subjects
Neural decoding from stereotactic EEG: accounting for electrode variability across subjects

Georgios Mentzelopoulos, Evangelos Chatzipantazis, Ashwin G Ramayya, Michelle Hedlund, Vivek Buch, Kostas Daniilidis, Konrad Kording, Flavia Vitale

Neural Information Processing Systems (NeurIPS) 2024

Neural decoding from stereotactic EEG: accounting for electrode variability across subjects

Georgios Mentzelopoulos, Evangelos Chatzipantazis, Ashwin G Ramayya, Michelle Hedlund, Vivek Buch, Kostas Daniilidis, Konrad Kording, Flavia Vitale

Neural Information Processing Systems (NeurIPS) 2024

All publications